Prefilled Syringes made of Polymer and Glass*)
Technik
Abstract
This article provides a comprehensive review of prefilled syringes (PFS), including their components, manufacturing processes, advantages and disadvantages and regulatory considerations.1) The article aims to provide readers with a thorough understanding of PFS, their characteristics, and application in the pharmaceutical industry.
PFS have become increasingly popular due to their convenience, dosage accuracy, lower risk of use errors, and shelf-life stability. With the growth of the biopharmaceutical industry, there is a growing demand for pre-fillable syringes for the administration of vaccines, monoclonal antibodies, xRNAs and other new modalities in development.
Correspondence:
Katharina Golly
Novartis Pharma AG, Novartis Campus, 4056 Basel
katharina.golly@novartis.com
 | Katharina Golly is a medical engineer and has 15+ years of experience in developing polymer and glass prefilled syringes and vials. Currently, she leads a team addressing needle clogging and strategizing for Novartis drug portfolio. She began at Schott, specializing in silicone-based coatings, and later established a vial kit competence center at Novartis. Katharina also trains technicians and engineers on vial and PFS topics at the ECA academy of Concept Heidelberg. |
Abstract
This article provides a comprehensive review of prefilled
