Rubrik: IT
(Treffer aus pharmind, Nr. 05, Seite 471 (2024))
Bunzel G | Bertram K | Erdmann N | Heitmann M | Jasper C
Use of synthetic data in AI development / Insights from a case study in Cryo-EM image analysis · Bunzel G
1, Bertram K
1, Erdmann N
2, Heitmann M
3, Jasper C
4 ·
1ATEM SD GmbH, Remscheid und Deloitte Wirtschaftsprüfungsgesellschaft GmbH, Düsseldorf und d-fine GmbH, Frankfurt und Charles River Microbial Solutions Germany GmbH, Kaarst
Unsupervised Machine Learning Synthetic Data Validation Adeno-Associated Viruses (AAV) Cryo-EM Personalized medicine and gene therapy are widely seen as mega trends in the pharmaceutical industry that will revolutionize the industry in the next few years [ 1 ]. One key factor for the success of gene therapy and personalized medicine, has been the use of adeno-associated viruses (AAV) DNA vectors. The AAV process has enabled the development of multiple high-value therapeutics with multi-million revenues per dose, as shown in tab. 1 [ 2 ]. Product Supplier Disease Area Licensed Price ($/dose) Lixturna Spark Therapeutics RPE65 retinal dystrophy 2017 0.85 million Zolgensma Novartis Spinal ...